منابع مشابه
Proteomics: New Developments in Target Discovery.
The Society for Medicines Research in collaboration with the Biological and Medicinal Chemistry sector of the Royal Society for Chemistry held a meeting on September 19, 2002, in London, United Kingdom to discuss proteomics in drug discovery. The meeting gave the most up-to-date overview of current progress in this new field, the challenges in silico, in vitro and in vivo, together with conside...
متن کاملTechnical advances in proteomics: new developments in data-independent acquisition
The ultimate aim of proteomics is to fully identify and quantify the entire complement of proteins and post-translational modifications in biological samples of interest. For the last 15 years, liquid chromatography-tandem mass spectrometry (LC-MS/MS) in data-dependent acquisition (DDA) mode has been the standard for proteomics when sampling breadth and discovery were the main objectives; multi...
متن کاملRecent developments in computational proteomics.
The mapping of the human genome was completed earlier this year and efforts are underway to understand the role of gene products (i.e. proteins) in biological pathways and human disease and to exploit their functional roles to derive protein therapeutics and protein-based drugs. A key component to the next revolution in the 'post-genomic' era will be the increasingly widespread use of protein s...
متن کاملSome New Developments in Small Area Estimation
Small area estimation has received a lot of attention in recent years due to growing demand for reliable small area statistics. Traditional area-specific estimators may not provide adequate precision because sample sizes in small areas are seldom large enough. This makes it necessary to employ indirect estimators based on linking models. Basic area level and unit level models have been extensiv...
متن کاملEukaryotic expression: developments for structural proteomics.
The production of sufficient quantities of protein is an essential prelude to a structure determination, but for many viral and human proteins this cannot be achieved using prokaryotic expression systems. Groups in the Structural Proteomics In Europe (SPINE) consortium have developed and implemented high-throughput (HTP) methodologies for cloning, expression screening and protein production in ...
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ژورنال
عنوان ژورنال: North Carolina Medical Journal
سال: 2007
ISSN: 0029-2559,0029-2559
DOI: 10.18043/ncm.68.2.119